To make the marinade, add 1 tablespoon apple cider vinegar, 2 teaspoons chili powder, 1 teaspoon garlic powder, 1 teaspoon onion powder, 1 teaspoon salt, ¼ teaspoon ground black pepper, and 2 tablespoons fresh lime juice to a small bowl and whisk to combine.
Add 2 pounds boneless skinless chicken thighs to a large ziplock bag and top with the marinade. Make sure all of the chicken is coated with the marinade, then press all the excess air out of the bag and seal. Place the marinating chicken in the refrigerator for at least 30 minutes, or up to 8 hours for deeper flavor.
Before cooking, preheat the grill to medium-high. Use tongs to transfer the chicken to the grill, then discard the marinade.
Grill the chicken for 6-8 minutes on each side or until cooked through and the thickest part of the chicken reaches 165 degrees Fahrenheit on a thermometer. Serve immediately.