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Meatloaf Sandwiches are the best combination meals with all your favorite toppings! They are juicy, full of flavor and perfect for lunch or dinner!

Serve these incredible tasting sandwiches with some fun sides and you got a meal everyone will love! Try Salad, Hush Puppies, and French Fries.

Grilled Meatloaf sandwich with cheese, tomato and lettuce.

Best Meatloaf Sandwich

This classic comfort food is tender, juicy, and packed with flavor. There is just something about a meatloaf sandwich that can take you back to the good old days, and make everything seem right with the world. Let’s face it we make meatloaf so we can have leftovers. Meatloaf is better the second day anyway, and I cannot think of a better way to eat them in this luscious sandwich. Oh, and this is not a cold meatloaf sandwich for the past, this is hot and heavenly!

Start with a meatloaf that is perfectly seasoned and baked to perfection and you cannot go wrong. You can use either this incredible instant pot recipe or this glazed meatloaf recipe and the sandwich will be destined for greatness. Pan grilling it will not only warm it up but give it a nice crust to the meatloaf that elevates your sandwich to the next level. You and your family are going to love this!

Ingredients For Leftover Meatloaf Sandwich

Start with your leftover meatloaf and go from there. Topping options are customizable and delicious.

  • Meatloaf: Of course we are using leftover meatloaf here. Either this incredible instant pot recipe or this Glazed Meatloaf will work.
  • Butter: Softened so it is spreadable on the bread.
  • Bread: I used crusty French bread for a crunchy, chewy texture.

Optional Toppings

Have your meatloaf sandwich plain or add to it with these fun toppings to spruce it up a bit. The toppings are optional and endless!

  • Lettuce
  • Tomato
  • Cheese
  • Sliced Red Onion

Let’s Make Your Sandwich!

This is as easy as a grilled cheese sandwich, only upscaled! It is simple to use leftover meatloaf then add your toppings and cook together for the perfect meatloaf sandwich!

  1. Make the Meatloaf ahead of time: Using the leftover meatloaf slices, add to a medium-sized skillet.
  2. Prepare Bread: Brush the side of the bread with butter and place facing down in the skillet. Top on side of the slice with cheese. Heat until melted and meatloaf is heated through.
  3. Create Your Sandwich! Assemble sandwich with desired toppings.
Grilling the meatloaf, and bread topped with cheese.

Tips for the Ultimate Meatloaf Sandwich

If your family loves meatloaf, make two, just so you can have leftovers to make these down home, comfort food morsels of awesomeness! This meatloaf sandwich will become another family favorite!

  • Slices of Meatloaf: How thick you slice your meatloaf matters. Think of who you are feeding, little mouths need thinner slices. Bigger mouths can handle a bigger slice.
  • Pan-frying: Pan-frying the meatloaf gives it that beautiful tasty crust on the meatloaf that you are going to love. Cooking it at the same time as the bread also means everything gets done at the same time! Everything will be nice and hot and melty! YUM!
  • Good Quality Bread: I used french bread for this sandwich which is a nice choice. You want bread that can hold up to the meatloaf and toppings and not fall apart on you while you eat it. Ciabatta, thick-sliced sourdough, and Italian bread are all good choices. Even a good thick-sliced white bread can be amazing. You can also use hamburger buns, pretzel buns, or ciabatta rolls.

Variations and Sides

Meatloaf sandwiches are great bases for customization and what you serve with it can turn this sandwich into a tasty meal. It is easy to make and adds another dinner to the menu!

  • Cheese: I highly recommend cheese, because everything tastes better with cheese! I used American but the possibilities are up to you. Try Monterey Jack, Cheddar, Provolone, Havarti, or even for kick, Pepper jack.
  • Sauce: I love sauces and how they can completely change the flavor and add to your dish. You can do all sorts of flavors here. Fry sauce, Yum Yum Sauce, BBQ Sauce, Chick-Fil-A Sauce, and for a kick Buffalo Sauce!
  • Toppings: Lettuce and tomato offer freshness that I love. Other options include pickles, grilled onions, mushrooms, bacon, jalapenos, and crispy onion straws.
  • Sides: A good side dish or two can really make a meal delicious. Roasted vegetables are yummy, try Brown Butter Roasted Carrots or Lemon Parmesan Asparagus. This Jiffy Corn Casserole is only 5 ingredients and super yummy. Of course, potatoes are always awesome with meatloaf, if you have leftover mashed potatoes, try these Mashed potato pancakes! Add a fruit salad like this Creamy Grape Salad or a Pasta Salad and you have you will have one heck of a meal!
Two halves of the grilled meatloaf sandwich stacked on top of each other.

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Meatloaf Sandwiches

5 from 1 vote
By: Alyssa Rivers
Meatloaf Sandwiches are the best combination of meals with all your favorite toppings! They are juicy, full of flavor, and perfect for lunch or dinner!
Prep Time: 10 minutes
Cook Time: 10 minutes
Total Time: 20 minutes
Servings: 4 sandwiches


Optional Toppings


  • Using the leftover meatloaf slices, add to a medium sized skillet.
  • Brush the side of the bread with butter and place facing down in the skillet. Top on side of the slice with cheese. Heat until melted and meatloaf is heated through.
  • Assemble sandwich with desired toppings.


Calories: 255kcalCarbohydrates: 28gProtein: 6gFat: 14gSaturated Fat: 8gTrans Fat: 1gCholesterol: 31mgSodium: 393mgPotassium: 105mgFiber: 2gSugar: 3gVitamin A: 356IUVitamin C: 1mgCalcium: 81mgIron: 2mg

Nutrition information is automatically calculated, so should only be used as an approximation.

Additional Info

Course: Main Course
Cuisine: American
Tried this recipe?Mention @alyssa_therecipecritic or tag #therecipecritic!

About Alyssa Rivers

Alyssa Rivers is the author of 'The Tried and True Cookbook', a professional food photographer and experienced recipe-developer. Having a passion for cooking, her tried and true recipes have been featured on Good Morning America, Today Food, Buzzfeed and more.

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Recipe Rating


  1. 5 stars
    a classic, long forgotten by me, a great time to bring it back, so thank you for the recipe, much appreciated!

  2. Even though I’m a pretty good cook, & crank out some super Shmancy meals, my crew is always happy when I serve them a good, old fashioned, hearty meatloaf. I have to make 2, since 1 is always for next day Sandwiches. There are 7 of us, so our meatloafs are huge. We like our Meatloaf Sandwiches served cold, on Poppy Seed Rolls, with either Provalone or Swiss Cheese, Bibb Lettuce, & Red Onion. A slice of Tomato, & a couple of sliced Pickles are optional. Some of us like ours w/Mayo, & others like Ketchup. Either way, they’re always a hit! Thank you Alyssa, for your terrific recipes, & helping to keep our families very well fed. 🌹